CD30/TNFRSF8 Rekombinanter Antikörper

CD30/TNFRSF8 Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

FC

Konjugation

APC Fluorescent Dye

CloneNo.

241330A12

Kat-Nr. : APC-FcA98124

Synonyme

CD30, 241330A12, Ki 1 antigen, Ki 1, D1S166E

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  FC experiment of human PBMCs using APC-FcA98124

  1x10^6 PHA treated human PBMCs were surface stained with 5 ul APC Anti-Human CD30/TNFRSF8 Rabbit RecAb (APC-FcA98124, Clone: 241330A12) (red) or 5 ul APC Rabbit IgG Isotype Control RecAb (APC-FcA98136, Clone: 240953C9) (blue). 1x10^6 untreated human PBMCs were surface stained with 5 ul APC Anti-Human CD30/TNFRSF8 Rabbit RecAb (APC-FcA98124, Clone: 241330A12) (black, dashed). Cells were not fixed.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in FC: PHA treated human PBMCs

Empfohlene Verdünnung

Anwendung	Verdünnung
This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 ul per 10^6 cells in a 100 µl suspension or 5 ul per 100 µl of whole blood.
Sample-dependent, check data in validation data gallery

Produktinformation

APC-FcA98124 bindet in FC CD30/TNFRSF8 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: Rekombinantes Protein
• Vollständiger Name: tumor necrosis factor receptor superfamily, member 8
• Berechnetes Molekulargewicht: 64 kDa
• GenBank-Zugangsnummer: NM_001243
• Gene symbol: CD30
• Gene ID (NCBI): 943
• Konjugation: APC Fluorescent Dye
• Excitation/Emission maxima wavelengths: 650 nm / 660 nm
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS with 0.09% sodium azide and 0.5% BSA
• Lagerungsbedingungen: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Hintergrundinformationen

CD30, also known as TNFRSF8 or Ki-1, is a transmembrane glycoprotein belonging to the tumor necrosis factor receptor superfamily. It is composed of an extracellular domain with six cysteine-rich repeats, a transmembrane segment, and an intracellular domain (PMID: 1310894). CD30 is expressed on a small subset of activated T and B lymphocytes, and a variety of lymphoid neoplasms, with the highest expression in classical Hodgkin's lymphoma and anaplastic large cell lymphoma (PMID: 9826579; 28885612). The CD30 ligand (CD30L or CD153) is a type II transmembrane glycoprotein of the tumor necrosis factor ligand superfamily (PMID: 8701986). Signal transduction of CD30/CD30L utilizes signal transducers, TNFR-associated factors (TRAF1, 2, 3 and 5) (PMID: 9826579).