CD300c Polyklonaler Antikörper

CD300c Polyklonal Antikörper für IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 32141-1-PBS

Synonyme

CMRF35, CMRF 35A, CMRF 35, CLM 6, CD300c molecule

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  IHC staining of human tonsillitis using 32141-1-AP (same clone as 32141-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 32141-1-AP (CD300c antibody) at dilution of 1:200 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 32141-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human tonsillitis using 32141-1-AP (same clone as 32141-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 32141-1-AP (CD300c antibody) at dilution of 1:200 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 32141-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

32141-1-PBS bindet in IHC, Indirect ELISA CD300c und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: Rekombinantes Protein
• Vollständiger Name: CD300c molecule
• Berechnetes Molekulargewicht: 224 aa, 25 kDa
• GenBank-Zugangsnummer: BC022279
• Gene symbol: CD300C
• Gene ID (NCBI): 10871
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CD300c is a member of the CD300 family of receptors, which are type I transmembrane proteins expressed in both myeloid and lymphoid lineages and modulate immune responses by their stimulatory and inhibitory capabilities (PMID: 30485414). CD300c, also known as CLM-6, CMRF-35 and IgSF16, is composed of an IgV-like extracellular domain, a transmembrane domain and a short cytoplasmic tail. It is expressed on the surface of monocytes, macrophages, dendritic cells, neutrophils, some T and B lymphocytes (PMID: 1349532; 30498497). CD300c has been reported as an activating receptor expressed on monocytes and that it has a potential role in inflammatory responses (PMID: 23571507). It has also been identified as a T cell co-inhibitory molecule (PMID: 30498497).