CD302 Rekombinanter Antikörper

CD302 Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Maus

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

242893C3

Kat-Nr. : 98434-2-PBS

Synonyme

CD302 antigen, Clec13a, C-type lectin domain family 13 member A, Type I transmembrane C-type lectin receptor DCL-1

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  FC experiment of Transfected HEK-293T using 98434-2-RR (same clone as 98434-2-PBS)

  1x10^6 HEK-293T cells (left) or CD302 transfected HEK-293T cells (right) were surface stained with 0.25 ug Anti-Mouse CD302 Rabbit RecAb (98434-2-RR, Clone: 242893C3) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98434-2-PBS in a different storage buffer formulation.

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  FC experiment of Transfected HEK-293T using 98434-2-RR (same clone as 98434-2-PBS)

  1x10^6 HEK-293T cells (left) or CD302 transfected HEK-293T cells (right) were surface stained with 0.25 ug Anti-Mouse CD302 Rabbit RecAb (98434-2-RR, Clone:242893C3) (red) or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98434-2-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

98434-2-PBS bindet in FC CD302 und zeigt Reaktivität mit Maus

• Getestete Reaktivität: Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: CD302 fusion protein Eg2660
• Vollständiger Name: CD302 antigen
• Berechnetes Molekulargewicht: 24 kDa
• GenBank-Zugangsnummer: NM_025422.4
• Gene symbol: Cd302
• Gene ID (NCBI): 66205
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C.

Hintergrundinformationen

CD302 is a C-type lectin receptor involved in cell adhesion and migration, as well as endocytosis and phagocytosis. In mice and humans, CD302 is primarily expressed in the liver, lungs, lymph nodes (LNs), spleen, and bone marrow. In CD302 gene knockout (CD302KO) mice, the migration frequency and number of myeloid dendritic cells (mDC) in CD302KO lymph nodes were reduced compared to the wild type, confirming the functional role of CD302 in mDC migration.