CD314/NKG2D Rekombinanter Antikörper

CD314/NKG2D Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Maus

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

250267G1

Kat-Nr. : 98481-2-PBS

Synonyme

CD314, Klrk1, Killer cell lectin-like receptor subfamily K member 1, NK cell receptor D, NKG2 D

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  FC experiment of mouse splenocytes using 98481-2-RR (same clone as 98481-2-PBS)

  1x10^6 mouse splenocytes were surface stained with 0.25 ug Anti-Mouse CD314/NKG2D Rabbit RecAb (98481-2-RR, Clone: 250267G1) or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were then stained with APC Anti-Mouse NK1.1. Cells were not fixed. This data was developed using the same antibody clone with 98481-2-PBS in a different storage buffer formulation.

• 

  FC experiment of mouse splenocytes using 98481-2-RR (same clone as 98481-2-PBS)

  1x10^6 mouse splenocytes were surface stained with 0.25 ug Anti-Mouse CD314/NKG2D Rabbit RecAb (98481-2-RR, Clone: 250267G1) (red) or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98481-2-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

98481-2-PBS bindet in FC CD314/NKG2D und zeigt Reaktivität mit Maus

• Getestete Reaktivität: Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: CD314/NKG2D fusion protein Eg3829
• Vollständiger Name: killer cell lectin-like receptor subfamily K, member 1
• Berechnetes Molekulargewicht: 27 kDa
• GenBank-Zugangsnummer: NM_033078.4
• Gene symbol: CD314
• Gene ID (NCBI): 27007
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C.

Hintergrundinformationen

CD314, also known as NKG2D or Killer cell lectin-like receptor subfamily K member 1 (KLRK1), is a type II lectin-like transmembrane stimulatory receptor (PMID: 8436421). In mice, CD314 is expressed on NK cells, activated CD8(+) T cells and macrophages, and subsets of TCR gamma delta (+) and NK1.1 (+) T cells (PMID: 12150888). Various subfamilies of MHC class I-related glycoproteins have been identified as the ligands for mouse CD314, including RAET1A, RAET1B, RAET1C, RAET1D, RAET1E, H60 and MULT1 (PMID: 31720075).