CD314/NKG2D Rekombinanter Antikörper

CD314/NKG2D Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Maus

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

250267G1

Kat-Nr. : 98481-2-RR

Synonyme

CD314, Klrk1, Killer cell lectin-like receptor subfamily K member 1, NK cell receptor D, NKG2 D

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  FC experiment of mouse splenocytes using 98481-2-RR

  1x10^6 mouse splenocytes were surface stained with 0.25 ug Anti-Mouse CD314/NKG2D Rabbit RecAb (98481-2-RR, Clone: 250267G1) or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were then stained with APC Anti-Mouse NK1.1. Cells were not fixed.

• 

  FC experiment of mouse splenocytes using 98481-2-RR

  1x10^6 mouse splenocytes were surface stained with 0.25 ug Anti-Mouse CD314/NKG2D Rabbit RecAb (98481-2-RR, Clone: 250267G1) (red) or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in FC: Maus-Splenozyten

Empfohlene Verdünnung

Anwendung	Verdünnung
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

98481-2-RR bindet in FC CD314/NKG2D und zeigt Reaktivität mit Maus

• Getestete Reaktivität: Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: CD314/NKG2D fusion protein Eg3829
• Vollständiger Name: killer cell lectin-like receptor subfamily K, member 1
• Berechnetes Molekulargewicht: 27 kDa
• GenBank-Zugangsnummer: NM_033078.4
• Gene symbol: CD314
• Gene ID (NCBI): 27007
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS with 0.09% sodium azide
• Lagerungsbedingungen: Store at 2 - 8°C. Stable for one year after shipment.

Hintergrundinformationen

CD314, also known as NKG2D or Killer cell lectin-like receptor subfamily K member 1 (KLRK1), is a type II lectin-like transmembrane stimulatory receptor (PMID: 8436421). In mice, CD314 is expressed on NK cells, activated CD8(+) T cells and macrophages, and subsets of TCR gamma delta (+) and NK1.1 (+) T cells (PMID: 12150888). Various subfamilies of MHC class I-related glycoproteins have been identified as the ligands for mouse CD314, including RAET1A, RAET1B, RAET1C, RAET1D, RAET1E, H60 and MULT1 (PMID: 31720075).