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CD32A/C Polyklonaler Antikörper

CD32A/C Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 25323-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of various lysates using CD32A/C Polyclonal antibody (25323-1-AP)

    WB analysis using 25323-1-AP (same clone as 25323-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 25323-1-AP (CD32A/C antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 25323-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

25323-1-PBS bindet in WB, Indirect ELISA CD32A/C und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen CD32A/C fusion protein Ag18123
Vollständiger Name Fc fragment of IgG, low affinity IIc, receptor for (CD32)
Berechnetes Molekulargewicht 323 aa, 36 kDa
Beobachtetes Molekulargewicht40 kDa
GenBank-ZugangsnummerBC137397
Gene symbol CD32A/C
Gene ID (NCBI) 9103
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

IgG Fc receptors (FcγRs) play important roles in immune responses. The low-affinity IgG Fc receptor, FcγRII (CD32), consists of a family of primarily cell membrane receptor proteins: CD32A, CD32B, and CD32C. They are encoded by the mRNA splice variants of three highly related genes: FCGR2A, FCGR2B, and FCGR2C (PMID: 30941127). CD32 is present on phagocytic cells such as macrophages and neutrophils, and is involved in the process of phagocytosis and clearing of immune complexes. This antibody raised against 254-323 aa of human CD32C (FCGR2C) can recognize both CD32A and CD32C forms.