CD336 Rekombinanter Antikörper

CD336 Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

242228B9

Kat-Nr. : 98371-1-PBS

Synonyme

NCR2, LY95, Lymphocyte antigen 95 homolog, Natural killer cell p44-related protein, NK cell activating receptor

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  FC experiment of Transfected HEK-293T using 98371-1-RR (same clone as 98371-1-PBS)

  1x10^6 HEK-293T cells or CD336 Transfected HEK-293T cells were stained with 0.25 ug Anti-Human CD336 Rabbit RecAb (98371-1-RR, Clone:242228B9) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C). This data was developed using the same antibody clone with 98371-1-PBS in a different storage buffer formulation.

• 

  FC experiment of Transfected HEK-293T using 98371-1-RR (same clone as 98371-1-PBS)

  1x10^6 HEK-293T cells or CD336 Transfected HEK-293T cells were stained with 0.25 ug Anti-Human CD336 Rabbit RecAb (98371-1-RR, Clone:242228B9) and PE-Conjugated Goat Anti-Rabbit IgG(H+L)(red), or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue). Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C). This data was developed using the same antibody clone with 98371-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

98371-1-PBS bindet in FC CD336 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: Rekombinantes Protein
• Vollständiger Name: natural cytotoxicity triggering receptor 2
• Berechnetes Molekulargewicht: 31 kDa
• GenBank-Zugangsnummer: NM_004828
• Gene symbol: CD336
• Gene ID (NCBI): 9436
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C.

Hintergrundinformationen

CD336, also named as NCR2, LY95 and NKp44, belongs to the natural cytotoxicity receptor (NCR) family. It is cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. It is expressed on activated human NK cells. CD336 displays a single extracellular Ig-like V domain and a transmembrane portion containing the charged residue (Lysine), likely involved in the association with KARAP/DAP12 molecules. The antibody is specific to CD336.