TREM-1/CD354 Rekombinanter Antikörper

TREM-1/CD354 Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Maus

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

240219H1

Kat-Nr. : 98022-1-RR

Synonyme

CD354/TREM-1, Trem1, TREM-1, TREM 1, CD354

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  FC experiment of mouse splenocytes using 98022-1-RR

  1x10^6 mouse splenocytes were surface stained with 0.25 ug Anti-Mouse TREM-1/CD354 Rabbit Recombinant Antibody (98022-1-RR, Clone:240219H1) or Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were then stained with APC Anti-Mouse Ly-6G/Ly-6C (Gr-1) (RB6-8C5) (APC-65140, Clone: RB6-8C5). Cells were not fixed.

• 

  Affinity and Kinetic Characterization of 98022-1-RR

  Biolayer interferometry (BLl) kinetic assays of 98022-1-RR against Mouse CD354/TREM-1 were performed. The affinity constant is 91.8 nM.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in FC: Maus-Splenozyten

Empfohlene Verdünnung

Anwendung	Verdünnung
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

98022-1-RR bindet in FC TREM-1/CD354 und zeigt Reaktivität mit Maus

• Getestete Reaktivität: Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: Rekombinantes Protein
• Vollständiger Name: triggering receptor expressed on myeloid cells 1
• Berechnetes Molekulargewicht: 25 kDa
• GenBank-Zugangsnummer: NM_021406.5
• Gene symbol: Trem1
• Gene ID (NCBI): 58217
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein A purfication
• Lagerungspuffer: PBS with 0.09% sodium azide
• Lagerungsbedingungen: Store at 2-8°C. Stable for one year after shipment.

Hintergrundinformationen

Triggering receptor expressed on myeloid cells 1 (TREM-1, also known as CD354) is a member of the immunoglobulin superfamily, which is expressed on neutrophils and monocytes. TREM1 plays a role in the innate immune system. TREM1 amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers.