CD36 Monoklonaler Antikörper

CD36 Monoklonal Antikörper für FC

Wirt / Isotyp

Maus / IgM, kappa

Getestete Reaktivität

human

Anwendung

FC

Konjugation

Unkonjugiert

Publikationen(1)

CloneNo.

SMΦ

Kat-Nr. : 65248-1-Ig

Synonyme

PAS 4, GPIV, GPIIIB, GP4, GP3B

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  FC experiment of human peripheral blood platelets using 65248-1-Ig

  100ul human peripheral blood platelets (diluted 1:2 in PBS) were surface stained with 0.2 ug Anti-Human CD36 (65248-1-Ig, Clone:SMΦ) or Mouse IgM Isotype Control (65243-1-Ig) and CoraLite®647-conjugated F(ab')2 Fragment Goat Anti-Mouse IgG (H+L) (SA00014-8). Cells were not fixed.

• 

  FC experiment of human peripheral blood platelets using 65248-1-Ig

  100ul human peripheral blood platelets (diluted 1:2 in PBS) were surface stained with 0.2 ug Anti-Human CD36 (65248-1-Ig, Clone:SMΦ) or Mouse IgM Isotype Control (65243-1-Ig) and CoraLite®647-conjugated F(ab')2 Fragment Goat Anti-Mouse IgG (H+L) (SA00014-8). Cells were not fixed.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in FC: human peripheral blood platelets

Empfohlene Verdünnung

Anwendung	Verdünnung
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Veröffentlichte Anwendungen

• FC: See 1 publications below

Produktinformation

65248-1-Ig bindet in FC CD36 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• In Publikationen genannte Reaktivität: human
• Wirt / Isotyp: Maus / IgM, kappa
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: k.A.
• Vollständiger Name: CD36 molecule (thrombospondin receptor)
• Berechnetes Molekulargewicht: 472 aa, 53 kDa
• GenBank-Zugangsnummer: BC008406
• Gene symbol: CD36
• Gene ID (NCBI): 948
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Affinitätsreinigung
• Lagerungspuffer: PBS with 0.09% sodium azide
• Lagerungsbedingungen: Store at 2-8°C. Stable for one year after shipment.

Hintergrundinformationen

CD36, also named as GP3B and GP4, is an 88-kDa membrane glycoprotein present on platelets, monocytes, erythroid precursors, endothelial cells, and several tumor cell lines. CD36 binds to collagen, thrombospondin, anionic phospholipids, long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport and oxidized LDL. CD36 may function as a cell adhesion molecule. It mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes. Mutation of CD36 will cause platelet glycoprotein IV deficiency which known as CD36 deficiency. Genetic variations in CD36 are associated with susceptibility to coronary heart disease type 7 (CHDS7).

Publikationen

Species	Application	Title
human	FC	Eur J Pharmacol; Obacunone Potentiated PD-1 Immunotherapy in Pancreatic Cancer by Mediating CD36; Authors - Chun-Yan Sang