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CD38 Rekombinanter Antikörper

CD38 Rekombinant Antikörper für IHC, Cytometric bead array, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

IHC, Cytometric bead array, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

241246E3

Kat-Nr. : 84070-3-PBS

Synonyme

241246E3, 2'-phospho-ADP-ribosyl cyclase, 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase, 2'-phospho-cyclic-ADP-ribose transferase, ADP ribosyl cyclase 1

Filter:
  • Immunohistochemistry (IHC) staining of human tonsillitis tissue using CD38 Recombinant antibody (84070-3-RR)

    IHC staining of human tonsillitis using 84070-3-RR (same clone as 84070-3-PBS)

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 84070-3-RR (CD38 antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 84070-3-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human tonsillitis tissue using CD38 Recombinant antibody (84070-3-RR)

    IHC staining of human tonsillitis using 84070-3-RR (same clone as 84070-3-PBS)

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 84070-3-RR (CD38 antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 84070-3-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 84070-3-RR

    Affinity and Kinetic Characterization of 84070-3-RR

    Biolayer interferometry (BLl) kinetic assays of 84070-3-RR against Human CD38 were performed. The affinity constant is 1.09 nM.

Geprüfte Anwendungen

Produktinformation

84070-3-PBS bindet in IHC, Cytometric bead array, Indirect ELISA CD38 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen CD38 fusion protein Eg0110
Vollständiger Name CD38 molecule
Berechnetes Molekulargewicht 300 aa, 34 kDa
GenBank-ZugangsnummerBC007964
Gene symbol CD38
Gene ID (NCBI) 952
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CD38, also known as ADP-ribosyl cyclase 1, is a type II transmembrane glycoprotein with a short N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites (PMID: 2319135). The extracellular domain of CD38 has bifunctional enzyme activities that catalyze synthesis of cyclic ADP ribose from nicotinamide adenine dinucleotide (NAD) and hydrolysis of cyclic ADP ribose to adenosine diphosphoribose (PMID: 10636863). CD38 is expressed on a variety of hematopoietic and non-hematopoietic cells and is involved in diverse processes such as generation of calcium-mobilizing metabolites, cell activation, and chemotaxis (PMID: 25938500).