CD38 Rekombinanter Antikörper

CD38 Rekombinant Antikörper für WB, ELISA

Wirt / Isotyp

Maus / IgG

Getestete Reaktivität

Kaninchen

Anwendung

WB, ELISA

Konjugation

Unkonjugiert

CloneNo.

241357C3

Kat-Nr. : 84689-1-MR

Synonyme

Cyclic ADP-ribose hydrolase 1, ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1, ADP-ribosyl cyclase 1, ADPRC 1, 2'-phospho-ADP-ribosyl cyclase

---

• 

  WB analysis of rabbit splenocytes using 84689-1-MR

  rabbit splenocytes were subjected to SDS PAGE followed by western blot with 84689-1-MR (CD38 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours.

• 

  WB analysis of rabbit serum using 84689-1-MR

  rabbit serum was subjected to SDS PAGE followed by western blot with 84689-1-MR (CD38 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours.

---

Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: rabbit splenocytes cells, rabbit serum

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:1000-1:4000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Produktinformation

84689-1-MR bindet in WB, ELISA CD38 und zeigt Reaktivität mit Kaninchen

• Getestete Reaktivität: Kaninchen
• Wirt / Isotyp: Maus / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: Fusionsprotein
• Vollständiger Name: CD38
• Beobachtetes Molekulargewicht: 45-50 kDa
• Gene symbol: CD38
• Gene ID (NCBI): 100009409
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein A purfication
• Lagerungspuffer: PBS with 0.02% sodium azide and 50% glycerol
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CD38, also known as ADP-ribosyl cyclase 1, is a type II transmembrane glycoprotein with a short N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites (PMID: 2319135). The extracellular domain of CD38 has bifunctional enzyme activities that catalyze synthesis of cyclic ADP ribose from nicotinamide adenine dinucleotide (NAD) and hydrolysis of cyclic ADP ribose to adenosine diphosphoribose (PMID: 10636863). CD38 is expressed on a variety of hematopoietic and non-hematopoietic cells and is involved in diverse processes such as generation of calcium-mobilizing metabolites, cell activation, and chemotaxis (PMID: 25938500).