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CD38 Rekombinanter Antikörper

CD38 Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

250107D9

Kat-Nr. : 85843-1-PBS

Synonyme

ADP ribosyl cyclase/cyclic ADP ribose hydrolase, CD38 antigen, Cyclic ADP ribose hydrolase 1

Filter:
  • Western Blot (WB) analysis of various lysates using CD38 Recombinant antibody (85843-1-RR)

    WB analysis using 85843-1-RR (same clone as 85843-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 85843-1-RR (Cd38 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85843-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

85843-1-PBS bindet in WB, Indirect ELISA CD38 und zeigt Reaktivität mit Maus, Ratten

Getestete Reaktivität Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen CD38 fusion protein Eg2915
Vollständiger Name CD38 antigen
Berechnetes Molekulargewicht34 kDa
Beobachtetes Molekulargewicht40-45 kDa
GenBank-ZugangsnummerNM_007646.5
Gene symbol Cd38
Gene ID (NCBI) 12494
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CD38, also known as ADP-ribosyl cyclase 1, is a type II transmembrane glycoprotein with a short N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites (PMID: 2319135). The extracellular domain of CD38 has bifunctional enzyme activities that catalyze synthesis of cyclic ADP ribose from nicotinamide adenine dinucleotide (NAD) and hydrolysis of cyclic ADP ribose to adenosine diphosphoribose (PMID: 10636863). CD38 is expressed on a variety of hematopoietic and non-hematopoietic cells and is involved in diverse processes such as generation of calcium-mobilizing metabolites, cell activation, and chemotaxis (PMID: 25938500).