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CD40L/CD154 Rekombinanter Antikörper

CD40L/CD154 Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

242847A5

Kat-Nr. : 85209-4-PBS

Synonyme

CD154, CD40L; CD154, CD40LG, CD40 ligand, CD40 L

Filter:
  • Western Blot (WB) analysis of human peripheral blood platelets using CD40L/CD154 Recombinant antibody (85209-4-RR)

    WB analysis of human peripheral blood platelets using 85209-4-RR (same clone as 85209-4-PBS)

    human peripheral blood platelets were subjected to SDS PAGE followed by western blot with 85209-4-RR (CD40L/CD154 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85209-4-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

85209-4-PBS bindet in WB, Indirect ELISA CD40L/CD154 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen Rekombinantes Protein
Vollständiger Name CD40 ligand
Berechnetes Molekulargewicht 261 aa, 29 kDa
Beobachtetes Molekulargewicht30 kDa
GenBank-ZugangsnummerBC071754
Gene symbol CD40 Ligand
Gene ID (NCBI) 959
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

The CD40 ligand (CD40L, TRAP, CD154), a member of the TNF superfamily of ligands, is expressed as either a 33 kDa transmembrane homologue or an 18 kDa soluble form (sCD154). CD40L is primarily expressed on activated CD4+ T cells and a small proportion of CD8+ T cells and platelets. It binds to CD40 on antigen-presenting cells (APC), which leads to many effects depending on the target cell type. Recent studies have suggested that CD40/CD40L interactions regulate oxidative stress and affect various signaling pathways in both the immunological and the cardiovascular systems. The CD40/CD40L system is also involved in tumorigenesis.