CD42a / GP9 Monoklonaler Antikörper

CD42a / GP9 Monoklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Maus / IgG2b

Getestete Reaktivität

human

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

2D4H1

Kat-Nr. : 67271-1-PBS

Synonyme

CD42a, Glycoprotein 9, glycoprotein IX (platelet), GP IX, GP9, GPIX, Platelet glycoprotein IX

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  WB analysis of human peripheral blood platelets using 67271-1-Ig (same clone as 67271-1-PBS)

  Human peripheral blood platelets were subjected to SDS PAGE followed by western blot with 67271-1-Ig (CD42a / GP9 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67271-1-PBS in a different storage buffer formulation.

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  IHC staining of human spleen using 67271-1-Ig (same clone as 67271-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human spleen tissue slide using 67271-1-Ig (CD42a / GP9 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67271-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human spleen using 67271-1-Ig (same clone as 67271-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human spleen tissue slide using 67271-1-Ig (CD42a / GP9 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67271-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

67271-1-PBS bindet in WB, IHC, Indirect ELISA CD42a / GP9 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Maus / IgG2b
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: CD42a / GP9 fusion protein Ag6132
• Vollständiger Name: glycoprotein IX (platelet)
• Berechnetes Molekulargewicht: 19 kDa
• Beobachtetes Molekulargewicht: 20 kDa
• GenBank-Zugangsnummer: BC030229
• Gene symbol: CD42a
• Gene ID (NCBI): 2815
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Platelet glycoprotein IX (GP9, also known as CD42a) is a relatively small surface glycoprotein present on platelets and megakaryocytes. GP9 forms a 1:1 non-covalent complex with GPIb (CD42b). The GPIb-V-IX complex functions as the vWF receptor and mediates vWF-dependent platelet adhesion to blood vessels. Defects in GP9 are a cause of Bernard-Soulier syndrome, also known as giant platelet disease.