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CD42c Polyklonaler Antikörper

CD42c Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 32462-1-PBS

Synonyme

GP1BB, GPIbB, GPIb beta, GP Ib beta, Antigen CD42b beta

Filter:
  • Western Blot (WB) analysis of various lysates using CD42c Polyclonal antibody (32462-1-AP)

    WB analysis using 32462-1-AP (same clone as 32462-1-PBS)

    Human peripheral blood platelets were subjected to SDS PAGE followed by western blot with 32462-1-AP (CD42c antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 32462-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

32462-1-PBS bindet in WB, Indirect ELISA CD42c und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen CD42c fusion protein Ag36521
Vollständiger Name glycoprotein Ib (platelet), beta polypeptide
Berechnetes Molekulargewicht22kDa，206aa
Beobachtetes Molekulargewicht26 kDa
GenBank-ZugangsnummerNM_000407.4
Gene symbol CD42c
Gene ID (NCBI) 2812
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CD42c, also known as platelet glycoprotein Ib beta chain (GP1BB), is a transmembrane protein containing a leucine-rich amino acid sequence (PMID: 3353370). CD42c is covalently linked to platelet glycoprotein Ib alpha chain (CD42b/GP1BA) to form GPIb, which is part of the Glycoprotein Ib-V-IX receptor (GPIb-V-IX) complex that constitutes the receptor for von Willebrand factor (VWF), and mediates platelet adhesion (PMID: 7660135). Mutations in the GP1BB gene have been associated with Bernard-Soulier syndrome, velocardiofacial syndrome, and giant platelet disorder.