CD44 Rekombinanter Antikörper

CD44 Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Maus

Anwendung

FC

Konjugation

CoraLux Violet 510 Fluorescent Dye

CloneNo.

242666F8

Kat-Nr. : CLV510-98359-2

Synonyme

242666F8, CD44 antigen, CDw44, CSPG8, ECMR III

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  FC experiment of mouse splenocytes using CLV510-98359-2

  1x10^6 mouse splenocytes were surface stained with APC Anti-Mouse CD62L, and 0.25 ug CoraLux Violet 510 Anti-Mouse CD44 Rabbit RecAb (CLV510-98359-2, Clone: 242666F8) or unstained. Cells were not fixed.

• 

  FC experiment of mouse splenocytes using CLV510-98359-2

  1x10^6 mouse splenocytes were surface stained with 0.25 ug CoraLux Violet 510 Anti-Mouse CD44 Rabbit RecAb (CLV510-98359-2, Clone: 242666F8) (red) or unstained (blue). Cells were not fixed.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in FC: Maus-Splenozyten

Empfohlene Verdünnung

Anwendung	Verdünnung
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

CLV510-98359-2 bindet in FC CD44 und zeigt Reaktivität mit Maus

• Getestete Reaktivität: Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: CD44 fusion protein Eg3159
• Vollständiger Name: CD44 antigen
• Berechnetes Molekulargewicht: 86 kDa
• GenBank-Zugangsnummer: NM_009851.2
• Gene symbol: Cd44
• Gene ID (NCBI): 12505
• Konjugation: CoraLux Violet 510 Fluorescent Dye
• Excitation/Emission maxima wavelengths: 410 nm / 501 nm
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS with 0.09% sodium azide
• Lagerungsbedingungen: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Hintergrundinformationen

CD44 is a type I transmembrane glycoprotein expressed on embryonic stem cells and in various levels on other cell types including connective tissues and bone marrow. CD44 expression is also upregulated in subpopulations of cancer cells and is recognized as a molecular marker for cancer stem cells (PMID: 29747682). It is a cell-surface receptor that mediates cell-cell and cell-matrix interactions through its affinity for hyaluronic acid (HA) and possibly also through its affinity for other ligands (PMID: 10694938). Adhesion with HA plays an important role in cell migration, tumor growth and progression. CD44 is also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis.