CD45 Rekombinanter Antikörper
CD45 Rekombinant Antikörper für WB, IHC, IF/ICC, IF-P, IF-Fro, ELISA
Wirt / Isotyp
Kaninchen / IgG
Getestete Reaktivität
human, Maus
Anwendung
WB, IHC, IF/ICC, IF-P, IF-Fro, ELISA
Konjugation
Unkonjugiert
CloneNo.
6O19
Kat-Nr. : 80297-1-PBS
Synonyme
Geprüfte Anwendungen
Produktinformation
80297-1-PBS bindet in WB, IHC, IF/ICC, IF-P, IF-Fro, ELISA CD45 und zeigt Reaktivität mit human, Maus
Getestete Reaktivität | human, Maus |
Wirt / Isotyp | Kaninchen / IgG |
Klonalität | Rekombinant |
Typ | Antikörper |
Immunogen | CD45 fusion protein Ag13712 |
Vollständiger Name | protein tyrosine phosphatase, receptor type, C |
Berechnetes Molekulargewicht | 1304 aa, 147 kDa |
Beobachtetes Molekulargewicht | 220-240 kDa |
GenBank-Zugangsnummer | BC014239 |
Gene symbol | CD45 |
Gene ID (NCBI) | 5788 |
Konjugation | Unkonjugiert |
Form | Liquid |
Reinigungsmethode | Protein-A-Reinigung |
Lagerungspuffer | PBS only |
Lagerungsbedingungen | Store at -80°C. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
CD45, also known as leukocyte common antigen (LCA), B220, and T200, is a 180-240 kD single chain type I membrane glycoprotein. It is a tyrosine phosphatase expressed on the plasma membrane of all hematopoietic cells, except erythrocytes and platelets. CD45 is a signaling molecule that regulates a variety of cellular processes including cell growth, differentiation, cell cycle, and oncogenic transformation. CD45 is one of the best negative selection markers for characterizing and/or isolating human mesenchymal stem cells from bone marrow and other sources. Along with the positive selection markers (such as CD29, CD44, CD90, CD105 and CD166), negative selection markers (such as CD34 and CD45) are used for MSC identification.