CD45 Rekombinanter Antikörper

CD45 Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Maus

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

240356D1

Kat-Nr. : 98035-1-RR

Synonyme

Ptprc, 240356D1, EC:3.1.3.48, LCA, L-CA

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  FC experiment of mouse splenocytes using 98035-1-RR

  1x10^6 mouse splenocytes were surface stained with 0.25 ug Anti-Mouse CD45 Rabbit Recombinant Antibody (98035-1-RR, Clone: 240356D1) (red) or 0.25 ug Isotype Control (blue), and PE-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). Cells were not fixed.

• 

  FC experiment of mouse splenocytes using 98035-1-RR

  1x10^6 mouse splenocytes were surface stained with 0.25 ug Anti-Mouse CD45 Rabbit Recombinant Antibody (98035-1-RR, Clone: 240356D1) or 0.25 ug Isotype Control, and PE-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). Cells were not fixed.

• 

  Affinity and Kinetic Characterization of 98035-1-RR

  Biolayer interferometry (BLl) kinetic assays of 98035-1 against Mouse CD45 were performed. The affinity constant is 0.787 nM.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in FC: Maus-Splenozyten

Empfohlene Verdünnung

Anwendung	Verdünnung
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

98035-1-RR bindet in FC CD45 und zeigt Reaktivität mit Maus

• Getestete Reaktivität: Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: CD45 fusion protein Eg0845
• Vollständiger Name: protein tyrosine phosphatase, receptor type, C
• Berechnetes Molekulargewicht: 145 kDa
• GenBank-Zugangsnummer: NM_001111316.2
• Gene symbol: CD45
• Gene ID (NCBI): 19264
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein A purfication
• Lagerungspuffer: PBS with 0.09% sodium azide
• Lagerungsbedingungen: Store at 2-8°C. Stable for one year after shipment.

Hintergrundinformationen

CD45, also known as protein tyrosine phosphatase, receptor type C, is a type I transmembrane protein expressed on the surface of all haematopoietic cells with the exception of erythrocytes and platelets (PMID: 3489673; 28615666). CD45 is a pan-haematopoietic cell marker and has been shown to be essential for T- and B-cell activation and signalling (PMID: 9429890; 16378097).