CD45RA Monoklonaler Antikörper

CD45RA Monoklonal Antikörper für IHC, IF-P, FC

Wirt / Isotyp

Maus / IgG1, kappa

Getestete Reaktivität

human

Anwendung

IHC, IF-P, FC

Konjugation

Unkonjugiert

CloneNo.

F8-11-13

Kat-Nr. : 65226-1-PBS

Synonyme

CD45, EC:3.1.3.48, F8-11-13, GP180, L CA



Geprüfte Anwendungen

Produktinformation

65226-1-PBS bindet in IHC, IF-P, FC CD45RA und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Maus / IgG1, kappa
Klonalität Monoklonal
Typ Antikörper
Immunogen Human T lymphocytes
Vollständiger Name protein tyrosine phosphatase, receptor type, C
Berechnetes Molekulargewicht 1304 aa, 147 kDa
GenBank-ZugangsnummerBC014239
Gene symbol CD45
Gene ID (NCBI) 5788
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-G-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C.

Hintergrundinformationen

CD45, also known as protein tyrosine phosphatase, receptor type C, is a type I transmembrane protein expressed on the surface of all haematopoietic cells with the exception of erythrocytes and platelets (PMID: 3489673; 28615666). CD45 is a pan-haematopoietic cell marker and has been shown to be essential for T- and B-cell activation and signalling (PMID: 9429890; 16378097). CD45 exists as multiple isoforms due to alternative splicing of three exons (4, 5, and 6, designated A, B, and C) in the extracellular domain (PMID: 12414720). CD45RA is expressed on naïve T cells, B cells, and monocytes (PMID: 1830500; 14687231).