CD45RA Monoklonaler Antikörper
CD45RA Monoklonal Antikörper für IHC, IF-P, FC
Wirt / Isotyp
Maus / IgG1, kappa
Getestete Reaktivität
human
Anwendung
IHC, IF-P, FC
Konjugation
Unkonjugiert
CloneNo.
F8-11-13
Kat-Nr. : 65226-1-PBS
Synonyme
Geprüfte Anwendungen
Produktinformation
65226-1-PBS bindet in IHC, IF-P, FC CD45RA und zeigt Reaktivität mit human
Getestete Reaktivität | human |
Wirt / Isotyp | Maus / IgG1, kappa |
Klonalität | Monoklonal |
Typ | Antikörper |
Immunogen | Human T lymphocytes |
Vollständiger Name | protein tyrosine phosphatase, receptor type, C |
Berechnetes Molekulargewicht | 1304 aa, 147 kDa |
GenBank-Zugangsnummer | BC014239 |
Gene symbol | CD45 |
Gene ID (NCBI) | 5788 |
Konjugation | Unkonjugiert |
Form | Liquid |
Reinigungsmethode | Protein-G-Reinigung |
Lagerungspuffer | PBS only |
Lagerungsbedingungen | Store at -80°C. |
Hintergrundinformationen
CD45, also known as protein tyrosine phosphatase, receptor type C, is a type I transmembrane protein expressed on the surface of all haematopoietic cells with the exception of erythrocytes and platelets (PMID: 3489673; 28615666). CD45 is a pan-haematopoietic cell marker and has been shown to be essential for T- and B-cell activation and signalling (PMID: 9429890; 16378097). CD45 exists as multiple isoforms due to alternative splicing of three exons (4, 5, and 6, designated A, B, and C) in the extracellular domain (PMID: 12414720). CD45RA is expressed on naïve T cells, B cells, and monocytes (PMID: 1830500; 14687231).