CD5 Rekombinanter Antikörper

CD5 Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

240428A12

Kat-Nr. : 98054-1-PBS

Synonyme

T1, Lymphocyte antigen T1/Leu-1, Lymphocyte antigen T1/Leu 1, LEU1, CD5 molecule

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  FC experiment of human PBMCs using 98054-1-RR (same clone as 98054-1-PBS)

  1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human CD5 Rabbit Recombinant Antibody (98054-1-RR, Clone: 240428A12) or 0.25 ug Isotype Control, and PE-conjugated Goat Anti-Rabbit IgG. Cells were then stained with CoraLite® Plus 647 Anti-Human CD19. Cells were not fixed. Lymphocytes were gated. This data was developed using the same antibody clone with 98054-1-PBS in a different storage buffer formulation.

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  FC experiment of human PBMCs using 98054-1-RR (same clone as 98054-1-PBS)

  1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human CD5 Rabbit Recombinant Antibody (98054-1-RR, Clone: 240428A12) (red) or 0.25 ug Isotype Control (blue), and PE-conjugated Goat Anti-Rabbit IgG. Cells were not fixed. Lymphocytes were gated. This data was developed using the same antibody clone with 98054-1-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 98054-1-RR

  Biolayer interferometry (BLl) kinetic assays of 98054-1-RR against Human CD5 were performed. The affinity constant is 0.27 nM.

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Geprüfte Anwendungen

Produktinformation

98054-1-PBS bindet in FC CD5 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: Rekombinantes Protein
• Vollständiger Name: CD5 molecule
• Berechnetes Molekulargewicht: 55 kDa
• GenBank-Zugangsnummer: NM_014207.4
• Gene symbol: CD5
• Gene ID (NCBI): 921
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein A purfication
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C.

Hintergrundinformationen

CD5 is a type I transmembrane glycoprotein of the scavenger receptor cysteine-rich family (PMID: 12403363). CD5 is expressed on a majority of thymocytes, mature T cells, B cell subsets, and peripheral blood dendritic cells (PMID: 9858516; 6156984; 10379049; 1384337). CD5 may act as a receptor in regulating T-cell proliferation. It functions as a negative regulator of TCR signaling during thymocyte development (PMID: 7542801).