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CD55 Rekombinanter Antikörper

CD55 Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Maus

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

241808C10

Kat-Nr. : 84519-4-PBS

Synonyme

DAF-GPI, Daf1, Daf, Complement decay-accelerating factor, GPI-anchored, Cd55a

Filter:
  • Western Blot (WB) analysis of various lysates using CD55 Recombinant antibody (84519-4-RR)

    WB analysis using 84519-4-RR (same clone as 84519-4-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84519-4-RR (CD55 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84519-4-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

84519-4-PBS bindet in WB, Indirect ELISA CD55 und zeigt Reaktivität mit Maus

Getestete Reaktivität Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen FusionProtein
Vollständiger Name CD55 antigen
Berechnetes Molekulargewicht43kDa
Beobachtetes Molekulargewicht58-70 kDa
GenBank-ZugangsnummerNM_010016.3
Gene symbol CD55
Gene ID (NCBI) 13136
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein A purfication
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CD55, also known as DAF, is a glycosylphosphatidylinositol (GPI)-anchored surface glycoprotein that is widely distributed on blood, stroma, epithelial, and endothelial cells (PMID: 7517044; 29503741). It can also exist as a soluble form in plasma, urine, saliva, tears, and synovial fluids (PMID: 29503741). CD55 is a complement regulatory protein (PMID: 2469439; 7517044). It inhibits formation of the C3 convertases through binding to C3b and C4b. It also binds the alternate pathway convertase C3bBb, the classical pathway convertase and C4b2a to accelerate their decay (PMID: 17289551). CD55 also serves as a receptor for coxsackieviruses B1, B3, and B5 and several enteroviruses (PMID: 7538177; 7517044). The observed molecular weight of mature CD55 varies between 50 to 100 kDa depending on the cell type. Different sizes of CD55 might be caused by alternative splicing or different glycosylation patterns (PMID: 29503741).