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CD6 Rekombinanter Antikörper

CD6 Rekombinant Antikörper für Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

241965D2

Kat-Nr. : 84508-3-PBS

Synonyme

CD6 molecule, Soluble CD6, T12, T-cell differentiation antigen CD6, TP120

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  • Affinity and Kinetic Characterization of 84508-3-PBS

    Affinity and Kinetic Characterization of 84508-3-PBS

    Biolayer interferometry (BLl) kinetic assays of 84508-3-PBS against Human CD6 were performed. The affinity constant is 86.7 pM.

Geprüfte Anwendungen

Produktinformation

84508-3-PBS bindet in Indirect ELISA CD6 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen CD6 fusion protein Eg2079
Vollständiger Name CD6 molecule
GenBank-ZugangsnummerBC033755
Gene symbol CD6
Gene ID (NCBI) 923
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CD6 is a type I transmembrane glycoprotein of 105-130 kDa that belongs to the scavenger receptor cysteine-rich superfamily (PMID: 21880988). It is composed of an extracellular region, which consists of three tandem SRCR domains, a transmembrane region, and a cytoplasmic tail devoid of intrinsic catalytic activity but harbouring several phosphorylatable residues suitable for intracellular signal transduction (PMID: 38139340; 23711376). CD6 is expressed by T cells, medullary thymocytes, a subset of B cells and NK cells, and in some cells of the brain (PMID: 1919444; 21178331). CD6 plays a role in lymphocyte activation, proliferation, and survival processes via interaction with its endogenous ligands.