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CD62L Rekombinanter Antikörper

CD62L Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Maus

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

250271C5

Kat-Nr. : 85903-1-PBS

Synonyme

L-selectin, CD62 antigen-like family member L, L selectin, LAM-1, LECAM 1

Filter:
  • Western Blot (WB) analysis of various lysates using CD62L Recombinant antibody (85903-1-RR)

    WB analysis using 85903-1-RR (same clone as 85903-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 85903-1-RR (CD62L antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85903-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

85903-1-PBS bindet in WB, Indirect ELISA CD62L und zeigt Reaktivität mit Maus

Getestete Reaktivität Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen CD62L fusion protein Eg3845
Vollständiger Name selectin, lymphocyte
Berechnetes Molekulargewicht42 kDa
Beobachtetes Molekulargewicht70-85 kDa
GenBank-ZugangsnummerNM_011346.2
Gene symbol CD62L
Gene ID (NCBI) 20343
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CD62L, also known as L-selectin or SELL, is a member of the selectin family of adhesion molecules that also include CD62E (E-selectin) and CD62P (P-selectin) (PMID: 2663882, 2473156, 1382078). CD62L is a highly glycosylated protein expressed on the surface of most leukocytes, including lymphocytes, neutrophils, monocytes, eosinophils, hematopoietic progenitor cells, and immature thymocytes (PMID: 1694883, 1688580). It mediates the binding of lymphocytes to high endothelial venules (HEV) of peripheral lymph nodes through interactions with a constitutively expressed ligand, and is also involved in lymphocyte, neutrophil, and monocyte attachment to endothelium at sites of inflammation (PMID: 1382078).