CD62P Rekombinanter Antikörper

CD62P Rekombinant Antikörper für FC

Wirt / Isotyp

Maus / IgG2a

Getestete Reaktivität

human

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

AK4

Kat-Nr. : 65587-1-MR

Synonyme

CD62, CD62P, FLJ45155, GMP 140, GMP140, GMRP, Granule membrane protein 140, GRMP, LECAM3, P selectin, PADGEM, PSEL, SELP

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  FC experiment of human peripheral blood platelets using 65587-1-MR

  1x10^6 thrombin treated human peripheral blood platelets were surface stained with 0.25 ug Anti-Human CD62P Mouse IgG2a Recombinant Antibody (65587-1-MR, Clone: AK4) (red) or Mouse IgG2a Isotype Control (65208-1-Ig, Clone: C1.18.4) (blue) and CoraLite®488-Conjugated Donkey Anti-Mouse IgG(H+L). Untreated human peripheral blood platelets were surface stained with 0.25 ug Anti-Human CD62P Mouse IgG2a Recombinant Antibody (65587-1-MR, Clone: AK4) and CoraLite®488-Conjugated Donkey Anti-Mouse IgG(H+L)(black). Cells were not fixed.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in FC: Thrombin treated human peripheral blood platelets

Empfohlene Verdünnung

Anwendung	Verdünnung
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

65587-1-MR bindet in FC CD62P und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Maus / IgG2a
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: Humane Thrombozyten
• Vollständiger Name: selectin P (granule membrane protein 140kDa, antigen CD62)
• Berechnetes Molekulargewicht: 830 aa, 91 kDa
• GenBank-Zugangsnummer: BC028067
• Gene symbol: CD62P
• Gene ID (NCBI): 6403
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS with 0.09% sodium azide
• Lagerungsbedingungen: Store at 2-8°C. Stable for one year after shipment.

Hintergrundinformationen

P-selectin, also known as GMP140 or CD62P, is a transmembrane glycoprotein that mediates the interaction of activated endothelial cells or platelets with leukocytes. It is an adhesion molecule involved in the pathogenesis of inflammation, thrombosis, and oncogenesis. P-selectin is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. Upon cell activation by agonists, P-selectin is transported rapidly to the cell surface.