CD62P Monoklonaler Antikörper

CD62P Monoklonal Antikörper für FC

Wirt / Isotyp

Maus / IgG1, kappa

Getestete Reaktivität

human, nicht-humane Primaten

Anwendung

FC

Konjugation

CoraLite® Plus 555 Fluorescent Dye

CloneNo.

AK4

Kat-Nr. : CL555-65164

Synonyme

CD62, CD62P, FLJ45155, GMP 140, GMP140, GMRP, Granule membrane protein 140, GRMP, LECAM3, P selectin, PADGEM, PSEL, SELP



Geprüfte Anwendungen

Erfolgreiche Detektion in FChuman peripheral blood platelets

Empfohlene Verdünnung

AnwendungVerdünnung
This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 µl per 10^6 cells in a 100 µl suspension or 5 µl per 100 µl of whole blood.
Sample-dependent, check data in validation data gallery

Produktinformation

CL555-65164 bindet in FC CD62P und zeigt Reaktivität mit human, nicht-humane Primaten

Getestete Reaktivität human, nicht-humane Primaten
Wirt / Isotyp Maus / IgG1, kappa
Klonalität Monoklonal
Typ Antikörper
Immunogen Humane Thrombozyten
Vollständiger Name selectin P (granule membrane protein 140kDa, antigen CD62)
Berechnetes Molekulargewicht 830 aa, 91 kDa
GenBank-ZugangsnummerBC028067
Gene symbol SELP
Gene ID (NCBI) 6403
Konjugation CoraLite® Plus 555 Fluorescent Dye
Excitation/Emission maxima wavelengths554 nm / 570 nm
Form Liquid
Reinigungsmethode Mit Protein-A-Affinitätschromatographie gereinigt
Lagerungspuffer PBS with 0.09% sodium azide and 0.5% BSA.
LagerungsbedingungenStore at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Hintergrundinformationen

P-selectin, also known as GMP140 or CD62P, is a transmembrane glycoprotein that mediates the interaction of activated endothelial cells or platelets with leukocytes. It is an adhesion molecule involved in the pathogenesis of inflammation, thrombosis, and oncogenesis. P-selectin is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. Upon cell activation by agonists, P-selectin is transported rapidly to the cell surface.

Protokolle

Produktspezifische Protokolle
FC protocol for CL Plus 555 CD62P antibody CL555-65164Protokoll herunterladen
Standard-Protokolle
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