- Featured Product
- KD/KO Validated
CD63 Polyklonaler Antikörper
CD63 Polyklonal Antikörper für
Wirt / Isotyp
Kaninchen / IgG
Getestete Reaktivität
human
Anwendung
Konjugation
CoraLite®594 Fluorescent Dye
Kat-Nr. : CL594-25682
Synonyme
Geprüfte Anwendungen
Produktinformation
CL594-25682 bindet in CD63 und zeigt Reaktivität mit human
| Getestete Reaktivität | human |
| Wirt / Isotyp | Kaninchen / IgG |
| Klonalität | Polyklonal |
| Typ | Antikörper |
| Immunogen | CD63 fusion protein Ag19690 |
| Vollständiger Name | CD63 molecule |
| Berechnetes Molekulargewicht | 26 kDa |
| Beobachtetes Molekulargewicht | 28-35 kDa |
| GenBank-Zugangsnummer | BC002349 |
| Gene symbol | CD63 |
| Gene ID (NCBI) | 967 |
| Konjugation | CoraLite®594 Fluorescent Dye |
| Excitation/Emission maxima wavelengths | 588 nm / 604 nm |
| Form | Liquid |
| Reinigungsmethode | Antigen-Affinitätsreinigung |
| Lagerungspuffer | PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA |
| Lagerungsbedingungen | Bei -20°C lagern. Vor Licht schützen. Nach dem Versand ein Jahr stabil. Aliquotieren ist bei -20oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
CD63 is a 30-60 kDa lysosomal membrane protein that belongs to the tetraspanin family. This protein plays many important roles in immuno-physiological functions. It mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. CD63 is expressed on activated platelets, thus it may function as a blood platelet activation marker. CD63 is a lysosomal membrane glycoprotein that is translocated to plasma membrane after platelet activation. The CD63 tetraspanin is highly expressed in the early stages of melanoma and decreases in advanced lesions, suggesting it as a possible suppressor of tumor progression. Deficiency of this protein is associated with Hermansky-Pudlak syndrome.
