CD63 Monoklonaler Antikörper
CD63 Monoklonal Antikörper für IF
Wirt / Isotyp
Maus / IgG1
Getestete Reaktivität
human
Anwendung
IF
Konjugation
CoraLite®594 Fluorescent Dye
CloneNo.
3D4D1
Kat-Nr. : CL594-67605
Synonyme
Galerie der Validierungsdaten
Geprüfte Anwendungen
| Erfolgreiche Detektion in IF | humanes Tonsillitisgewebe |
Empfohlene Verdünnung
| Anwendung | Verdünnung |
|---|---|
| Immunfluoreszenz (IF) | IF : 1:50-1:500 |
| Sample-dependent, check data in validation data gallery | |
Produktinformation
CL594-67605 bindet in IF CD63 und zeigt Reaktivität mit human
| Getestete Reaktivität | human |
| Wirt / Isotyp | Maus / IgG1 |
| Klonalität | Monoklonal |
| Typ | Antikörper |
| Immunogen | CD63 fusion protein Ag19690 |
| Vollständiger Name | CD63 molecule |
| Berechnetes Molekulargewicht | 26 kDa |
| Beobachtetes Molekulargewicht | 35 kDa |
| GenBank-Zugangsnummer | BC002349 |
| Gene symbol | CD63 |
| Gene ID (NCBI) | 967 |
| Konjugation | CoraLite®594 Fluorescent Dye |
| Excitation/Emission maxima wavelengths | 588 nm / 604 nm |
| Form | Liquid |
| Reinigungsmethode | Protein-G-Reinigung |
| Lagerungspuffer | BS mit 50% Glyzerin, 0,05% Proclin300, 0,5% BSA, pH 7,3. |
| Lagerungsbedingungen | Bei -20°C lagern. Vor Licht schützen. Nach dem Versand ein Jahr stabil. Aliquotieren ist bei -20oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
CD63, known as LAMP-3, is a 30-60 kDa lysosomal membrane protein that belongs to the tetraspanin family. This protein plays many important roles in immuno-physiological functions. It mediate signal transduction events that play a role in the regulation of cell development, activation and motility. CD63 is expressed on activated platelets, thus it may function as a blood platelet activation marker. CD63 is a lysosomal membrane glycoprotein that is translocated to plasma membrane after platelet activation. The CD63 tetraspanin is highly expressed in the early stages of melanoma and decreases in advanced lesions, suggesting it as a possible suppressor of tumor progression. Deficiency of this protein is associated with Hermansky-Pudlak syndrome.
Protokolle
| Produktspezifische Protokolle | |
|---|---|
| IF protocol for CL594 CD63 antibody CL594-67605 | Protokoll herunterladen |
| Standard-Protokolle | |
|---|---|
| Klicken Sie hier, um unsere Standardprotokolle anzuzeigen |
Rezensionen
The reviews below have been submitted by verified Proteintech customers who received an incentive forproviding their feedback.
FH Amr (Verified Customer) (10-07-2021) | Anti CD63 CL488 and CL594 were validated in Blood plasma exosomes and in bone marrow. The antibodies seem to recogize their specific epitopes very well both extra and intracellularly. Strongly recommended.!
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