CD64 Rekombinanter Antikörper

CD64 Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Maus

Anwendung

FC

Konjugation

Biotin

CloneNo.

241809A6

Kat-Nr. : Biotin-FcA98218

Synonyme

Fcg1, Fc-gamma RI, Fcgr1, FcRI, High affinity immunoglobulin gamma Fc receptor I

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  FC experiment of mouse bone marrow cells using Biotin-FcA98218

  1x10^6 mouse bone marrow cells were surface stained with FcZero-rAb™ APC Anti-Mouse CD11b, and 0.25 ug Biotin Anti-Mouse CD64 Rabbit RecAb (Biotin-FcA98218, Clone: 241809A6) or FcZero-rAb™ Biotin Rabbit IgG Isotype Control Recombinant Antibody (Biotin-FcA98136, Clone: 240953C9), and PE-conjugated streptavidin. Cells were not fixed.

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  FC experiment of mouse bone marrow cells using Biotin-FcA98218

  1x10^6 mouse bone marrow cells were surface stained with 0.25 ug Biotin Anti-Mouse CD64 Rabbit RecAb (Biotin-FcA98218, Clone: 241809A6) (red) or FcZero-rAb™ Biotin Rabbit IgG Isotype Control Recombinant Antibody (Biotin-FcA98136, Clone: 240953C9) (blue), and PE-conjugated streptavidin. Cells were not fixed.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in FC: Maus-Knochenmarkzellen

Empfohlene Verdünnung

Anwendung	Verdünnung
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

Biotin-FcA98218 bindet in FC CD64 und zeigt Reaktivität mit Maus

• Getestete Reaktivität: Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: CD64 fusion protein Eg2107
• Vollständiger Name: Fc receptor, IgG, high affinity I
• Berechnetes Molekulargewicht: 45 kDa
• GenBank-Zugangsnummer: NM_010186.5
• Gene symbol: Fcgr1
• Gene ID (NCBI): 14129
• Konjugation: Biotin
• Excitation/Emission maxima wavelengths: -
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS with 0.09% sodium azide
• Lagerungsbedingungen: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Hintergrundinformationen

Fcγ receptor comprise a multigene family of integral membrane glycoproteins that exhibit complex activation or inhibitory effects on cell functions after aggregation by complexed immunoglobulin G (IgG) (PMID: 17005690 ). CD64, also known as FcγRIA, is a high-affinity receptor for the Fc region of IgG. It is expressed by monocytes/macrophages, activated neutrophils, dendritic cells, and early myeloid cells (PMID: 23293080; 19642859; 7680917). CD64 functions in both innate and adaptive immune responses.