CD71 Monoklonaler Antikörper

CD71 Monoklonal Antikörper für FC

Wirt / Isotyp

Ratte / IgG2a, kappa

Getestete Reaktivität

Maus und mehr (1)

Anwendung

IF, FC

Konjugation

Unkonjugiert

Publikationen(2)

CloneNo.

RI7217

Kat-Nr. : 65289-1-Ig

Synonyme

Tfrc, RI7217, TFR, TFR1, TR

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  FC experiment of C57BL/6 mouse bone marrow cells using 65289-1-Ig

  1X10^6 C57BL/6 mouse bone marrow cells were surface co-stained with APC Anti-Mouse TER-119 (TER-119) and 0.5 ug Anti-Mouse CD71 (65289-1-Ig, Clone: RI7217) or 0.5 ug Rat IgG2a Isotype Control (2A3), and FITC anti-Rat IgG2a Antibody at dilution 1:100. Cells were not fixed.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in FC: C57BL/6 mouse bone marrow cells

Empfohlene Verdünnung

Anwendung	Verdünnung
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Veröffentlichte Anwendungen

• IF: See 1 publications below
• FC: See 1 publications below

Produktinformation

65289-1-Ig bindet in IF, FC CD71 und zeigt Reaktivität mit Maus

• Getestete Reaktivität: Maus
• In Publikationen genannte Reaktivität: human, Maus
• Wirt / Isotyp: Ratte / IgG2a, kappa
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: DMSO induced Friend erythroleukemia 745.6
• Vollständiger Name: transferrin receptor
• GenBank-Zugangsnummer: BC054522
• Gene symbol: CD71
• Gene ID (NCBI): 22042
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Affinitätsreinigung
• Lagerungspuffer: PBS with 0.09% sodium azide
• Lagerungsbedingungen: Store at 2-8°C. Stable for one year after shipment.

Hintergrundinformationen

CD71, also known as transferrin receptor protein 1 (TfR1), is a transmembrane glycoprotein composed of two disulfide-linked monomers, each of 90 kDa molecular weight. Each monomer binds one holo-transferrin molecule, creating an iron-Tf-TfR complex that enters the cell by endocytosis. CD71 is present on actively proliferating cells and is essential for iron transport into proliferating cells.

Publikationen

Species	Application	Title
mouse	FC	Cell Chem Biol; Anti-tumor immunotherapy using engineered bacterial outer membrane vesicles fused to lysosome-targeting chimeras mediated by transferrin receptor; Authors - Ling-Yan Su
human	IF	Cancer Discov; Functional reprogramming of neutrophils within the brain tumor microenvironment by hypoxia-driven histone lactylation; Authors - Alessio Ugolini