CD71 Rekombinanter Antikörper

CD71 Rekombinant Antikörper für FC

Wirt / Isotyp

Ratte / IgG2a

Getestete Reaktivität

Maus

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

RI7217

Kat-Nr. : 65654-1-PBS

Synonyme

Tfrc, TFR, TFR1, TR, transferrin receptor

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  FC experiment of mouse bone marrow cells using 65654-1-TR (same clone as 65654-1-PBS)

  1x10^6 mouse bone marrow cells were surface stained with 0.25 ug Anti-Mouse CD71 (RI7217) Rat IgG2a RecAb (65654-1-TR, Clone: RI7217) or Rat IgG2a Isotype Control (2A3) (65209-1-Ig, Clone: 2A3), and FITC anti-Rat IgG2a antibody. Cells were then stained with APC Anti-Mouse TER-119. Cells were not fixed. This data was developed using the same antibody clone with 65654-1-PBS in a different storage buffer formulation.

• 

  FC experiment of mouse bone marrow cells using 65654-1-TR (same clone as 65654-1-PBS)

  1x10^6 mouse bone marrow cells were surface stained with 0.25 ug Anti-Mouse CD71 (RI7217) Rat IgG2a RecAb (65654-1-TR, Clone: RI7217) (red) or Rat IgG2a Isotype Control (2A3) (65209-1-Ig, Clone: 2A3) (blue), and FITC anti-Rat IgG2a antibody. Cells were not fixed. This data was developed using the same antibody clone with 65654-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

65654-1-PBS bindet in FC CD71 und zeigt Reaktivität mit Maus

• Getestete Reaktivität: Maus
• Wirt / Isotyp: Ratte / IgG2a
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: k.A.
• Vollständiger Name: transferrin receptor
• GenBank-Zugangsnummer: BC054522
• Gene symbol: CD71
• Gene ID (NCBI): 22042
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C.

Hintergrundinformationen

CD71, also known as transferrin receptor protein 1 (TfR1), is a transmembrane glycoprotein composed of two disulfide-linked monomers, each of 90 kDa molecular weight. Each monomer binds one holo-transferrin molecule, creating an iron-Tf-TfR complex that enters the cell by endocytosis. CD71 is present on actively proliferating cells and is essential for iron transport into proliferating cells.