CD71 Rekombinanter Antikörper

CD71 Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

250738F12

Kat-Nr. : 81793-5-PBS

Synonyme

p90, sTfR, T9, TFR, TFR1

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  WB analysis using 81793-5-RR (same clone as 81793-5-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 81793-5-RR (CD71 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 81793-5-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 81793-5-PBS

  Biolayer interferometry (BLl) kinetic assays of 81793-5-PBS against Human CD71 were performed. The affinity constant is 47.1 pM.

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Geprüfte Anwendungen

Produktinformation

81793-5-PBS bindet in WB, Indirect ELISA CD71 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: CD71 fusion protein Eg0339
• Vollständiger Name: transferrin receptor (p90, CD71)
• Berechnetes Molekulargewicht: 85 kDa
• Beobachtetes Molekulargewicht: 85-90 kDa
• Gene symbol: CD71
• Gene ID (NCBI): 7037
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CD71, also known as transferrin receptor protein 1 (TfR1), is a transmembrane glycoprotein composed of two disulfide-linked monomers, each of 90 kDa molecular weight. Each monomer binds one holo-transferrin molecule creating an iron-Tf-TfR complex that enters the cell by endocytosis. CD71 is present on actively proliferating cells and is essential for iron transport into proliferating cells.