CD71 Rekombinanter Antikörper

CD71 Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Maus

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

242122F6

Kat-Nr. : 98272-1-PBS

Synonyme

Tfrc, transferrin receptor, TR, TFR1, TFR

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  FC experiment of mouse bone marrow cells using 98272-1-RR (same clone as 98272-1-PBS)

  1x10^6 mouse bone marrow cells were surface stained with 0.25 ug Anti-Mouse CD71 Rabbit Recombinant Antibody (98272-1-RR, Clone: 242122F6) or 0.25 ug Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were co-stained with APC Anti-Mouse TER-119. Cells were not fixed. This data was developed using the same antibody clone with 98272-1-PBS in a different storage buffer formulation.

• 

  FC experiment of mouse bone marrow cells using 98272-1-RR (same clone as 98272-1-PBS)

  1x10^6 mouse bone marrow cells were surface stained with 0.25 ug Anti-Mouse CD71 Rabbit Recombinant Antibody (98272-1-RR, Clone: 242122F6)(red) or 0.25 ug Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98272-1-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 98272-1-RR

  Biolayer interferometry (BLl) kinetic assays of 98272-1-RR against Mouse CD71 were performed. The affinity constant is 0.88 nM.

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Geprüfte Anwendungen

Produktinformation

98272-1-PBS bindet in FC CD71 und zeigt Reaktivität mit Maus

• Getestete Reaktivität: Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: Rekombinantes Protein
• Vollständiger Name: transferrin receptor
• Berechnetes Molekulargewicht: 86kDa
• GenBank-Zugangsnummer: NM_011638.4
• Gene symbol: CD71
• Gene ID (NCBI): 22042
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein A purfication
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C.

Hintergrundinformationen

CD71, also known as transferrin receptor protein 1 (TfR1), is a transmembrane glycoprotein composed of two disulfide-linked monomers, each of 90 kDa molecular weight. Each monomer binds one holo-transferrin molecule creating an iron-Tf-TfR complex that enters the cell by endocytosis. CD71 is present on actively proliferating cells and is essential for iron transport into proliferating cells.