CD73 Rekombinanter Antikörper

CD73 Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Maus

Anwendung

FC

Konjugation

FITC Plus Fluorescent Dye

CloneNo.

241541G9

Kat-Nr. : FITC-98199

Synonyme

241541G9, 5'-deoxynucleotidase, 5'-NT, 5'-nucleotidase, EC:3.1.3.99

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  FC experiment of mouse splenocytes using FITC-98199

  1x10^6 mouse splenocytes were surface stained with APC Anti-Mouse CD3, and 0.25 ug FITC Plus Anti-Mouse CD73 Rabbit RecAb (FITC-98199, Clone:241541G9) or FITC Plus Rabbit IgG Isotype Control RecAb (FITC-98136, Clone: 240953C9). Cells were not fixed.

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  FC experiment of mouse splenocytes using FITC-98199

  1x10^6 mouse splenocytes were surface stained with 0.25 ug FITC Plus Anti-Mouse CD73 Rabbit RecAb (FITC-98199, Clone:241541G9) (red) or FITC Plus Rabbit IgG Isotype Control RecAb (FITC-98136, Clone: 240953C9) (blue). Cells were not fixed.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in FC: Maus-Splenozyten

Empfohlene Verdünnung

Anwendung	Verdünnung
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

FITC-98199 bindet in FC CD73 und zeigt Reaktivität mit Maus

• Getestete Reaktivität: Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: CD73 fusion protein Eg1389
• Vollständiger Name: 5' nucleotidase, ecto
• Berechnetes Molekulargewicht: 64kDa
• GenBank-Zugangsnummer: NM_011851.4
• Gene symbol: Nt5e
• Gene ID (NCBI): 23959
• Konjugation: FITC Plus Fluorescent Dye
• Excitation/Emission maxima wavelengths: 495 nm / 524 nm
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS with 0.09% sodium azide
• Lagerungsbedingungen: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Hintergrundinformationen

CD73 is a membrane-bound enzyme that catalyzes the extracellular hydrolysis of adenosine monophosphate (AMP) to produce adenosine. It is expressed on various immune cells, including T cells, B cells, dendritic cells, and regulatory T cells (Tregs). CD73 works in conjunction with CD39 to break down extracellular ATP into adenosine, creating an immunosuppressive environment that can inhibit the function of cytotoxic T cells and natural killer (NK) cells. This process is essential for immune tolerance and the resolution of inflammation. CD73 is also an important player in controlling tumor progression.