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CD74 Rekombinanter Antikörper

CD74 Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

250520B12

Kat-Nr. : 86023-5-PBS

Synonyme

Class-II-associated invariant chain peptide, DHLAG, HLADG, HLA-DR antigens-associated invariant chain, Ia antigen-associated invariant chain

Filter:
  • Western Blot (WB) analysis of various lysates using CD74 Recombinant antibody (86023-5-RR)

    WB analysis using 86023-5-RR (same clone as 86023-5-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 86023-5-RR (CD74 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86023-5-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

86023-5-PBS bindet in WB, Indirect ELISA CD74 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen CD74 fusion protein Eg1945
Vollständiger Name CD74 molecule, major histocompatibility complex, class II invariant chain
Berechnetes Molekulargewicht26 kDa
Beobachtetes Molekulargewicht 37 kDa
GenBank-ZugangsnummerNM_001025159.3
Gene symbol CD74
Gene ID (NCBI) 972
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CD74, also known as MHC class II invariant chain Ii or HLA-DR-associated invariant chain, is a non-polymorphic type II transmembrane glycoprotein. CD74 is mainly distributed in B cells, monocytes, Langerhans cells, dendritic cells and thymic epithelial cells, and is also expressed in epithelial cells. CD74 plays a key role in MHC class II antigen processing and also serves as a cell surface receptor for the macrophage cytokine MIF. CD74 plays an important role in cardiovascular diseases such as atherosclerosis, ischemic heart disease, and myocardial hypertrophy.(PMID: 15475450; PMID: 27752708; PMID: 38992165; PMID: 36712241).