CD79a Rekombinanter Antikörper

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• KD/KO Validated

CD79a Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

230167A8

Kat-Nr. : 82747-6-PBS

Synonyme

230167A8, B-cell antigen receptor complex-associated protein alpha chain, MB 1, MB 1 membrane glycoprotein, MB1

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  WB analysis using 82747-6-RR (same clone as 82747-6-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 82747-6-RR (CD79a antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 82747-6-PBS in a different storage buffer formulation.

• 

  WB analysis of Raji using 82747-6-RR (same clone as 82747-6-PBS)

  WB result of CD79a antibody (82747-6-RR; 1:3000; incubated at room temperature for 1.5 hours) with sh-Control and sh-CD79a transfected Raji cells. This data was developed using the same antibody clone with 82747-6-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 82747-6-RR

  Biolayer interferometry (BLl) kinetic assays of 82747-6-RR against Human CD79A were performed. The affinity constant is 31.3 nM.

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Geprüfte Anwendungen

Produktinformation

82747-6-PBS bindet in WB, Indirect ELISA CD79a und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: CD79a fusion protein Ag17924
• Vollständiger Name: CD79a molecule, immunoglobulin-associated alpha
• Berechnetes Molekulargewicht: 226 aa, 25 kDa
• Beobachtetes Molekulargewicht: 38-45 kDa
• GenBank-Zugangsnummer: BC113733
• Gene symbol: CD79A
• Gene ID (NCBI): 973
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CD79a, also named as B-cell antigen receptor complex-associated protein alpha chain or MB-1 membrane glycoprotein, is a 226 amino acid protein, which contains one ITAM domain and one Ig-like C2-type (immunoglobulin-like) domain. CD79A is expressed in B cells and localizes in the cell membrane. CD79A is required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. CD79A is also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells.