CD79b Rekombinanter Antikörper

CD79b Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

241273B7

Kat-Nr. : 98075-1-RR

Synonyme

IGB, Ig beta, B-cell-specific glycoprotein B29, B-cell antigen receptor complex-associated protein beta chain, B29

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  FC experiment of human PBMCs using 98075-1-RR

  1x10^6 human PBMCs were stained with CoraLite® Plus 647 Anti-Human CD19 (4G7) Mouse IgG2a Recombinant Antibody (CL647-65562, Clone: 4G7) and 0.25 ug Anti-Human CD79b Rabbit Recombinant Antibody (98075-1-RR, Clone:241273B7), or Isotype Control. Cells were not fixed.

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  FC experiment of human PBMCs using 98075-1-RR

  1x10^6 human PBMCs were stained with 0.25 ug Anti-Human CD79b Rabbit Recombinant Antibody (98075-1-RR, Clone:241273B7) (red), or Isotype Control(blue). Cells were not fixed.

• 

  FC experiment of human PBMCs using 98075-1-RR

  1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human CD79b Rabbit Recombinant Antibody (98075-1-RR, Clone:241273B7) and PE-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L), and 0.25 ug CoraLite® Plus 647 Anti-Human CD19 (4G7) Mouse IgG2a Recombinant Antibody (CL647-65562, Clone: 4G7), and 0.25 ug Isotype Control. Cells were not fixed.

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  Affinity and Kinetic Characterization of 98075-1-RR

  Biolayer interferometry (BLl) kinetic assays of 98075-1-RR against Human CD79b were performed. The affinity constant is 1.41 nM.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in FC: humane PBMCs

Empfohlene Verdünnung

Anwendung	Verdünnung
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

98075-1-RR bindet in FC CD79b und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: Rekombinantes Protein
• Vollständiger Name: CD79b molecule, immunoglobulin-associated beta
• Berechnetes Molekulargewicht: 229 aa, 26 kDa
• GenBank-Zugangsnummer: BC032651
• Gene symbol: CD79B
• Gene ID (NCBI): 974
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein A purfication
• Lagerungspuffer: PBS with 0.09% sodium azide
• Lagerungsbedingungen: Store at 2 - 8°C. Stable for one year after shipment.

Hintergrundinformationen

CD79 molecule encompasses two transmembrane proteins, CD79a and CD79b, which form a disulfide-linked heterodimer and are members of the immunoglobulin (Ig) gene superfamily (PMID: 2033258; 1375264; 2304550). CD79b molecule (also known as B29, IGB, AGM6, and Igbeta) is expressed almost exclusively on B cells and B-cell neoplasms, influencing antigen internalization and increasing antigen presentation efficiency (PMID: 7552998). CD79b mutation could be a key biomarker for DLBCL disease progression (PMID: 36182550).