CD82 Rekombinanter Antikörper

CD82 Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

241765F7

Kat-Nr. : 98278-1-PBS

Synonyme

CD82, KAI1, Metastasis suppressor Kangai-1, IA4, CD82,KAI1, CD 82

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  FC experiment of human PBMCs using 98278-1-RR (same clone as 98278-1-PBS)

  1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human CD82 Rabbit Recombinant Antibody (98278-1-RR, Clone: 241765F7) or 0.25 ug Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were co-stained with APC Anti-Human CD3 (OKT3) Mouse IgG2a Recombinant Antibody (APC-65569, Clone: OKT3). Cells were not fixed. Lymphocytes were gated. This data was developed using the same antibody clone with 98278-1-PBS in a different storage buffer formulation.

• 

  FC experiment of human PBMCs using 98278-1-RR (same clone as 98278-1-PBS)

  1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human CD82 Rabbit Recombinant Antibody (98278-1-RR, Clone: 241765F7) (red) or 0.25 ug Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. Lymphocytes were gated. This data was developed using the same antibody clone with 98278-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

98278-1-PBS bindet in FC CD82 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: Rekombinantes Protein
• Vollständiger Name: CD82 molecule
• Berechnetes Molekulargewicht: 30 kDa
• GenBank-Zugangsnummer: NM_002231.4
• Gene symbol: CD82
• Gene ID (NCBI): 3732
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein A purfication
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C.

Hintergrundinformationen

CD82 is a membrane glycoprotein and belongs to the tetraspanin superfamily, many of which are implicated in the regulation of cell motility, morphology, fusion, signaling, fertilization, and differentiation. CD82 was originally identified as a suppressor of metastasis located on human chromosome 11p11.2 in prostate carcinoma. The majority of evidence indicates that CD82 expression is downregulated or abolished in a variety of malignant tumors. CD82 is present at high levels in human monocyte and macrophage lineages and in various epithelial cells in the prostate, lung, pancreas and many other tissues. In epithelial cells, CD82 is implicated in diverse biological processes such as cell adhesion, migration, apoptosis and morphogenesis.