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CD83 Monoklonaler Antikörper

CD83 Monoklonal Antikörper für Cytometric bead array, Indirect ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

human

Anwendung

Cytometric bead array, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

2G3A3

Kat-Nr. : 60744-3-PBS

Synonyme

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  • Cytometric bead array standard curve of MP51077-2

    Cytometric bead array standard curve of MP51077-2

    Cytometric bead array standard curve of MP51077-2, CD83 Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 60744-3-PBS. Detection antibody: 60744-2-PBS. Standard:Ag27435. Range: 0.195-100 ng/mL.

Geprüfte Anwendungen

Produktinformation

60744-3-PBS bindet in Cytometric bead array, Indirect ELISA CD83 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Maus / IgG1
Klonalität Monoklonal
Typ Antikörper
Immunogen CD83 fusion protein Ag27435
Vollständiger Name CD83 molecule
Berechnetes Molekulargewicht 205 aa, 23 kDa
GenBank-ZugangsnummerBC030830
Gene symbol CD83
Gene ID (NCBI) 9308
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-G-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CD83 is a member of the immunoglobulin (Ig) superfamily, consisting of an extracellular V-type Ig-like domain, a transmembrane domain, and a cytoplasmic tail. CD83 is one of the most prominent markers for fully matured dendritic cells (DCs) (PMID: 17334966). It is also found on the surface of other activated hematopoietic cells, including lymphocytes, monocytes, macrophages, and neutrophils (PMID: 31231400; 17334966). CD83 regulates the maturation, activation, and homeostasis of numerous immune cells (PMID: 31231400; 32362900). CD83 can also expressed as a soluble form. Soluble CD83 can bind to DCs and inhibit their maturation (PMID: 17334966; 12403928).