CD83 Rekombinanter Antikörper
CD83 Rekombinant Antikörper für WB, Sandwich ELISA, Indirect ELISA, Sample test
Wirt / Isotyp
Kaninchen / IgG
Getestete Reaktivität
human
Anwendung
WB, Sandwich ELISA, Indirect ELISA, Sample test
Konjugation
Unkonjugiert
CloneNo.
241855G5
Kat-Nr. : 84796-3-PBS
Synonyme
Geprüfte Anwendungen
Produktinformation
84796-3-PBS bindet in WB, Sandwich ELISA, Indirect ELISA, Sample test CD83 und zeigt Reaktivität mit human
| Getestete Reaktivität | human |
| Wirt / Isotyp | Kaninchen / IgG |
| Klonalität | Rekombinant |
| Typ | Antikörper |
| Immunogen | CD83 fusion protein Eg2033 |
| Vollständiger Name | CD83 molecule |
| Berechnetes Molekulargewicht | 23 kDa |
| Beobachtetes Molekulargewicht | 40-45 kDa |
| GenBank-Zugangsnummer | NM_004233.4 |
| Gene symbol | CD83 |
| Gene ID (NCBI) | 9308 |
| Konjugation | Unkonjugiert |
| Form | Liquid |
| Reinigungsmethode | Protein-A-Reinigung |
| Lagerungspuffer | PBS only |
| Lagerungsbedingungen | Store at -80°C. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
CD83 is a member of the immunoglobulin (Ig) superfamily, consisting of an extracellular V-type Ig-like domain, a transmembrane domain, and a cytoplasmic tail. CD83 is one of the most prominent markers for fully matured dendritic cells (DCs) (PMID: 17334966). It is also found on the surface of other activated hematopoietic cells, including lymphocytes, monocytes, macrophages, and neutrophils (PMID: 31231400; 17334966). CD83 regulates the maturation, activation, and homeostasis of numerous immune cells (PMID: 31231400; 32362900). CD83 can also expressed as a soluble form. Soluble CD83 can bind to DCs and inhibit their maturation (PMID: 17334966; 12403928).





