CD83 Rekombinanter Antikörper

CD83 Rekombinant Antikörper für FC

Wirt / Isotyp

Maus / IgG2a

Getestete Reaktivität

human, nicht-humane Primaten

Anwendung

FC

Konjugation

Biotin

CloneNo.

HB15e

Kat-Nr. : Biotin-65581

Synonyme

B cell activation protein, B-cell activation protein, BL11, CD83 antigen, CD83 molecule

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  FC experiment of human monocyte-derived mature dendritic cells using Biotin-65581

  1x10^6 human monocyte-derived mature dendritic cells were surface stained with 0.25 ug Biotin Anti-Human CD83 (HB15e) Mouse IgG2a RecAb (Biotin-65581, Clone: HB15e) (red) or unstained (blue), and CoraLite®488-conjugated streptavidin. Cells were not fixed.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in FC: human monocyte-derived mature dendritic cells

Empfohlene Verdünnung

Anwendung	Verdünnung
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

Biotin-65581 bindet in FC CD83 und zeigt Reaktivität mit human, nicht-humane Primaten

• Getestete Reaktivität: human, nicht-humane Primaten
• Wirt / Isotyp: Maus / IgG2a
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: Humane CD83-transfizierte Cos-Zellen
• Vollständiger Name: CD83 molecule
• Berechnetes Molekulargewicht: 205 aa, 23 kDa
• GenBank-Zugangsnummer: BC030830
• Gene symbol: CD83
• Gene ID (NCBI): 9308
• Konjugation: Biotin
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS with 0.09% sodium azide
• Lagerungsbedingungen: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Hintergrundinformationen

CD83 is a member of the immunoglobulin (Ig) superfamily, consisting of an extracellular V-type Ig-like domain, a transmembrane domain, and a cytoplasmic tail. CD83 is one of the most prominent markers for fully matured dendritic cells (DCs) (PMID: 17334966). It is also found on the surface of other activated hematopoietic cells, including lymphocytes, monocytes, macrophages, and neutrophils (PMID: 31231400; 17334966). CD83 regulates the maturation, activation, and homeostasis of numerous immune cells (PMID: 31231400; 32362900). CD83 can also expressed as a soluble form. Soluble CD83 can bind to DCs and inhibit their maturation (PMID: 17334966; 12403928).