CD84 Rekombinanter Antikörper

CD84 Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

241345A3

Kat-Nr. : 98108-1-RR

Synonyme

Hly9-beta, Hly9 beta, hCD84, Cell surface antigen MAX.3, CD84 molecule

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  FC experiment of human PBMCs using 98108-1-RR

  1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human CD84 Rabbit Recombinant Antibody (98108-1-RR, Clone: 241345A3) or Isotype Control, and PE-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). Cells were then stained with CoraLite® Plus 647 Anti-Human CD4 (OKT4). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed.

• 

  FC experiment of human PBMCs using 98108-1-RR

  1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human CD84 Rabbit Recombinant Antibody (98108-1-RR, Clone: 241345A3) or Isotype Control, and PE-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed.

• 

  Affinity and Kinetic Characterization of 98108-1-RR

  Biolayer interferometry (BLl) kinetic assays of 98108-1-RR against Human CD84 were performed. The affinity constant is 1.14 nM.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in FC: humane PBMCs

Empfohlene Verdünnung

Anwendung	Verdünnung
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

98108-1-RR bindet in FC CD84 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: Rekombinantes Protein
• Vollständiger Name: CD84 molecule
• Berechnetes Molekulargewicht: 345 aa, 39 kDa
• GenBank-Zugangsnummer: BC020063
• Gene symbol: CD84
• Gene ID (NCBI): 8832
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein A purfication
• Lagerungspuffer: PBS with 0.09% sodium azide
• Lagerungsbedingungen: Store at 2 - 8°C. Stable for one year after shipment.

Hintergrundinformationen

CD84, also known as SLAMF5, is a member of the CD2 subfamily of the immunoglobulin receptor superfamily (PMID: 9310491). CD84 is a single-chain type-I glycoprotein composed of two extracellular Ig-like domains, a hydrophobic transmembrane region, and a cytoplasmic domain. It is broadly expressed on almost all leukocyte subsets. CD84 functions as a homophilic adhesion molecule, whose signaling can activate or inhibit leukocyte function depending on the cell type and its stage of activation or differentiation (PMID: 30522694).