CD86 Rekombinanter Antikörper
CD86 Rekombinant Antikörper für FC
Wirt / Isotyp
Maus / IgG2a
Getestete Reaktivität
human
Anwendung
FC
Konjugation
Unkonjugiert
CloneNo.
BU63
Kat-Nr. : 65592-1-PBS
Synonyme
Geprüfte Anwendungen
Produktinformation
65592-1-PBS bindet in FC CD86 und zeigt Reaktivität mit human
Getestete Reaktivität | human |
Wirt / Isotyp | Maus / IgG2a |
Klonalität | Rekombinant |
Typ | Antikörper |
Immunogen | B-lymphoblastoide Zelllinie ARH 77 |
Vollständiger Name | CD86 molecule |
Berechnetes Molekulargewicht | 329 aa, 38 kDa |
GenBank-Zugangsnummer | BC040261 |
Gene symbol | CD86 |
Gene ID (NCBI) | 942 |
Konjugation | Unkonjugiert |
Form | Liquid |
Reinigungsmethode | Protein-A-Reinigung |
Lagerungspuffer | PBS only |
Lagerungsbedingungen | Store at -80°C. |
Hintergrundinformationen
CD86 (also known as B7.2) is a costimulatory molecule belonging to the immunoglobulin superfamily. Primarily expressed on antigen-presenting cells (APCs), including B cells, dendritic cells, and macrophages, CD86 is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of CD86 with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of CD86 with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response.