CD86 Rekombinanter Antikörper
CD86 Rekombinant Antikörper für FC
Wirt / Isotyp
Maus / IgG2a
Getestete Reaktivität
human
Anwendung
FC
Konjugation
Unkonjugiert
CloneNo.
BU63
Kat-Nr. : 65592-1-PBS
Synonyme
Geprüfte Anwendungen
Produktinformation
65592-1-PBS bindet in FC CD86 und zeigt Reaktivität mit human
| Getestete Reaktivität | human | 
| Wirt / Isotyp | Maus / IgG2a | 
| Klonalität | Rekombinant | 
| Typ | Antikörper | 
| Immunogen | B-lymphoblastoide Zelllinie ARH 77 | 
| Vollständiger Name | CD86 molecule | 
| Berechnetes Molekulargewicht | 329 aa, 38 kDa | 
| GenBank-Zugangsnummer | BC040261 | 
| Gene symbol | CD86 | 
| Gene ID (NCBI) | 942 | 
| Konjugation | Unkonjugiert | 
| Form | Liquid | 
| Reinigungsmethode | Protein-A-Reinigung | 
| Lagerungspuffer | PBS only | 
| Lagerungsbedingungen | Store at -80°C. | 
Hintergrundinformationen
CD86 (also known as B7.2) is a costimulatory molecule belonging to the immunoglobulin superfamily. Primarily expressed on antigen-presenting cells (APCs), including B cells, dendritic cells, and macrophages, CD86 is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of CD86 with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of CD86 with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response.





