CD86 Rekombinanter Antikörper
CD86 Rekombinant Antikörper für FC
Wirt / Isotyp
Kaninchen / IgG
Getestete Reaktivität
Maus
Anwendung
FC
Konjugation
Unkonjugiert
CloneNo.
230476B8
Kat-Nr. : 98025-1-RR
Synonyme
Geprüfte Anwendungen
Erfolgreiche Detektion in FC | LPS treated mouse splenocytes |
Empfohlene Verdünnung
Anwendung | Verdünnung |
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This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, check data in validation data gallery |
Produktinformation
98025-1-RR bindet in FC CD86 und zeigt Reaktivität mit Maus
Getestete Reaktivität | Maus |
Wirt / Isotyp | Kaninchen / IgG |
Klonalität | Rekombinant |
Typ | Antikörper |
Immunogen | Fusionsprotein |
Vollständiger Name | CD86 antigen |
Berechnetes Molekulargewicht | 35 kDa |
GenBank-Zugangsnummer | NM_019388 |
Gene symbol | Cd86 |
Gene ID (NCBI) | 12524 |
Konjugation | Unkonjugiert |
Form | Liquid |
Reinigungsmethode | Protein A purfication |
Lagerungspuffer | PBS with 0.09% sodium azide |
Lagerungsbedingungen | Store at 2-8°C. Stable for one year after shipment. |
Hintergrundinformationen
CD86 (also known as B7-2) is a costimulatory molecule belonging to the immunoglobulin superfamily. Primarily expressed on antigen-presenting cells (APCs), including B cells, dendritic cells, and macrophages, CD86 is the ligand for two proteins at the cell surface of T cells, CD28 antigen and CTLA-4. Binding of CD86 with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of CD86 with CTLA-4 negatively regulates T-cell activation and diminishes the immune response. (PMID: 7513726; 1847722; 11029388; 27591335)
Protokolle
PRODUKTSPEZIFISCHE PROTOKOLLE | |
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FC protocol for CD86 antibody 98025-1-RR | Download protocol |
STANDARD-PROTOKOLLE | |
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Klicken Sie hier, um unsere Standardprotokolle anzuzeigen |