CD86 Rekombinanter Antikörper
CD86 Rekombinant Antikörper für FC
Wirt / Isotyp
Kaninchen / IgG
Getestete Reaktivität
human
Anwendung
FC
Konjugation
APC Fluorescent Dye
CloneNo.
240429C6
Kat-Nr. : APC-FcA98043
Synonyme
Geprüfte Anwendungen
Erfolgreiche Detektion in FC | humane PBMCs |
Empfohlene Verdünnung
Anwendung | Verdünnung |
---|---|
This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 ul per 10^6 cells in a 100 µl suspension or 5 ul per 100 µl of whole blood. | |
Sample-dependent, check data in validation data gallery |
Produktinformation
APC-FcA98043 bindet in FC CD86 und zeigt Reaktivität mit human
Getestete Reaktivität | human |
Wirt / Isotyp | Kaninchen / IgG |
Klonalität | Rekombinant |
Typ | Antikörper |
Immunogen | CD86 fusion protein Eg0966 |
Vollständiger Name | CD86 molecule |
Berechnetes Molekulargewicht | 329 aa, 38 kDa |
GenBank-Zugangsnummer | NM_175862 |
Gene symbol | CD86 |
Gene ID (NCBI) | 942 |
Konjugation | APC Fluorescent Dye |
Excitation/Emission maxima wavelengths | 650 nm / 660 nm |
Form | Liquid |
Reinigungsmethode | Protein-A-Reinigung |
Lagerungspuffer | PBS with 0.09% sodium azide and 0.5% BSA |
Lagerungsbedingungen | Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. |
Hintergrundinformationen
CD86 (also known as B7-2) is a costimulatory molecule belonging to the immunoglobulin superfamily. Primarily expressed on antigen-presenting cells (APCs), including B cells, dendritic cells, and macrophages, CD86 is the ligand for two proteins at the cell surface of T cells, CD28 antigen and CTLA-4. Binding of CD86 with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of CD86 with CTLA-4 negatively regulates T-cell activation and diminishes the immune response. (PMID: 7513726; 1847722; 11029388; 27591335)
Protokolle
PRODUKTSPEZIFISCHE PROTOKOLLE | |
---|---|
FC protocol for APC CD86 antibody APC-FcA98043 | Download protocol |
STANDARD-PROTOKOLLE | |
---|---|
Klicken Sie hier, um unsere Standardprotokolle anzuzeigen |