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CD8a Rekombinanter Antikörper

CD8a Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

243018F5

Kat-Nr. : 86063-1-PBS

Synonyme

CD8, CD8a molecule, Leu2, MAL, p32

Filter:
  • Western Blot (WB) analysis of various lysates using CD8a Recombinant antibody (86063-1-RR)

    WB analysis using 86063-1-RR (same clone as 86063-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 86063-1-RR (CD8A antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86063-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 86063-1-RR

    Affinity and Kinetic Characterization of 86063-1-RR

    Biolayer interferometry (BLl) kinetic assays of 86063-1-RR against Human CD8a were performed. The affinity constant is 1.42 nM.

Geprüfte Anwendungen

Produktinformation

86063-1-PBS bindet in WB, Indirect ELISA CD8a und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen CD8a fusion protein Eg0819
Vollständiger Name CD8a molecule
Berechnetes Molekulargewicht26 kDa
Beobachtetes Molekulargewicht25 kDa
GenBank-ZugangsnummerNM_001145873.1
Gene symbol CD8A
Gene ID (NCBI) 925
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CD8 is a transmembrane glycoprotein that is predominantly expressed on the surface of cytotoxic T cells, and can also be found on natural killer cells, cortical thymocytes, and dendritic cells. CD8 serves as a co-receptor for the T cell receptor (TCR). Both CD8 and TCR recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. CD8 plays a role in T cell development and activation of mature T cells. This antibody is raised against 22-182 aa of human CD8a, the alpha chain of CD8 molecule.