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CD8b Monoklonaler Antikörper

CD8b Monoklonal Antikörper für IHC, Indirect ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

human

Anwendung

IHC, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

4B3B8

Kat-Nr. : 68432-1-PBS

Synonyme

CD8, 4B3B8, Ly3, Leu2, CD8B1

Filter:
  • Immunohistochemistry (IHC) staining of human breast cancer tissue using CD8b Monoclonal antibody (68432-1-Ig)

    IHC staining of human breast cancer using 68432-1-Ig (same clone as 68432-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 68432-1-Ig (CD8b antibody) at dilution of 1:2000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 68432-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human breast cancer tissue using CD8b Monoclonal antibody (68432-1-Ig)

    IHC staining of human breast cancer using 68432-1-Ig (same clone as 68432-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 68432-1-Ig (CD8b antibody) at dilution of 1:2000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 68432-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

68432-1-PBS bindet in IHC, Indirect ELISA CD8b und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Maus / IgG1
Klonalität Monoklonal
Typ Antikörper
Immunogen CD8b fusion protein Ag16925
Vollständiger Name CD8b molecule
Berechnetes Molekulargewicht 243 aa, 27 kDa
GenBank-ZugangsnummerBC100913
Gene symbol CD8B
Gene ID (NCBI) 926
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-G-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CD8b (T-cell surface glycoprotein CD8 beta chain) is an integral membrane glycoprotein that forms disulfide-linked heterodimers with CD8a (CD8 alpha chain). The CD8 alpha/beta heterodimer is the predominant CD8 complex expressed on the cell surface (PMID: 1534146; 2111591). CD8 is a transmembrane glycoprotein predominantly expressed on cytotoxic T cells and can also be found on natural killer cells, cortical thymocytes, and dendritic cells. CD8 serves as a co-receptor for the T cell receptor (TCR). Both CD8 and TCR recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. CD8 plays a role in T cell development and activation of mature T cells.