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CD8b Rekombinanter Antikörper

CD8b Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Maus

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

250480F2

Kat-Nr. : 86024-1-PBS

Synonyme

Cd8b1, Ly-3, Lymphocyte antigen 3, Lyt3, Lyt-3

Filter:
  • Western Blot (WB) analysis of various lysates using CD8b Recombinant antibody (86024-1-RR)

    WB analysis using 86024-1-RR (same clone as 86024-1-PBS)

    Mouse thymus tissue was subjected to SDS PAGE followed by western blot with 86024-1-RR (CD8 beta antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86024-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of various lysates using CD8b Recombinant antibody (86024-1-RR)

    WB analysis using 86024-1-RR (same clone as 86024-1-PBS)

    Mouse spleen tissue was subjected to SDS PAGE followed by western blot with 86024-1-RR (CD8 beta antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86024-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

86024-1-PBS bindet in WB, Indirect ELISA CD8b und zeigt Reaktivität mit Maus

Getestete Reaktivität Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen CD8b fusion protein Eg4275
Vollständiger Name CD8 antigen, beta chain 1
Berechnetes Molekulargewicht24 kDa
Beobachtetes Molekulargewicht26-30 kDa
GenBank-ZugangsnummerNM_009858.2
Gene symbol Cd8b1
Gene ID (NCBI) 12526
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CD8b (T-cell surface glycoprotein CD8 beta chain) is an integral membrane glycoprotein that forms disulfide-linked heterodimers with CD8a (CD8 alpha chain). The CD8 alpha/beta heterodimer is the predominant CD8 complex expressed on the cell surface (PMID: 1534146; 2111591). CD8 is a transmembrane glycoprotein predominantly expressed on cytotoxic T cells and can also be found on natural killer cells, cortical thymocytes, and dendritic cells. CD8 serves as a co-receptor for the T cell receptor (TCR). Both CD8 and TCR recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. CD8 plays a role in T cell development and activation of mature T cells.