CD8b Rekombinanter Antikörper

CD8b Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

FC

Konjugation

Biotin

CloneNo.

241326A7

Kat-Nr. : Biotin-98103

Synonyme

CD8, 241326A7, CD8b molecule, CD8B1, Leu2

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  FC experiment of human PBMCs using Biotin-98103

  1x10^6 human PBMCs were surface stained with 5 ul Biotin Anti-Human CD8b Rabbit RecAb (Biotin-98103, Clone:241326A7) and PE-conjugated streptavidin, or unstained. Cells were co-stained with APC Anti-Human CD3 (UCHT1) Mouse IgG2a Recombinant Antibody (APC-65570, Clone: UCHT1). Cells were not fixed.

• 

  FC experiment of human PBMCs using Biotin-98103

  1x10^6 human PBMCs were surface stained with 5 ul Biotin Anti-Human CD8b Rabbit RecAb (Biotin-98103, Clone: 241326A7) and PE-conjugated streptavidin (red), or unstained (blue). Cells were not fixed.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in FC: humane PBMCs

Empfohlene Verdünnung

Anwendung	Verdünnung
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

Biotin-98103 bindet in FC CD8b und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: Rekombinantes Protein
• Vollständiger Name: CD8b molecule
• Berechnetes Molekulargewicht: 243 aa, 27 kDa
• GenBank-Zugangsnummer: BC100913
• Gene symbol: CD8B
• Gene ID (NCBI): 926
• Konjugation: Biotin
• Excitation/Emission maxima wavelengths: -
• Form: Liquid
• Reinigungsmethode: Protein A purfication
• Lagerungspuffer: PBS with 0.09% sodium azide and 0.5% BSA
• Lagerungsbedingungen: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Hintergrundinformationen

CD8b (T-cell surface glycoprotein CD8 beta chain) is an integral membrane glycoprotein that forms disulfide-linked heterodimers with CD8a (CD8 alpha chain). The CD8 alpha/beta heterodimer is the predominant CD8 complex expressed on the cell surface (PMID: 1534146; 2111591). CD8 is a transmembrane glycoprotein predominantly expressed on the surface of cytotoxic T cells and can also be found on natural killer cells, cortical thymocytes, and dendritic cells. CD8 serves as a co-receptor for the T cell receptor (TCR). Both CD8 and TCR recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. CD8 plays a role in T cell development and activation of mature T cells.