CD93 Rekombinanter Antikörper

CD93 Rekombinant Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

242464D2

Kat-Nr. : 84945-4-PBS

Synonyme

C1QR1, Matrix-remodeling-associated protein 4, C1qRp, C1qR(p), C1qR

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  WB analysis of HUVEC using 84945-4-RR (same clone as 84945-4-PBS)

  HUVEC cells were subjected to SDS PAGE followed by western blot with 84945-4-RR (CD93 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84945-4-PBS in a different storage buffer formulation.

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  IHC staining of human tonsillitis using 84945-4-RR (same clone as 84945-4-PBS)

  Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 84945-4-RR (CD93 antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 84945-4-PBS in a different storage buffer formulation.

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  IHC staining of human tonsillitis using 84945-4-RR (same clone as 84945-4-PBS)

  Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 84945-4-RR (CD93 antibody) at dilution of 1:1000 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 84945-4-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

84945-4-PBS bindet in WB, IHC, Indirect ELISA CD93 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: Rekombinantes Protein
• Vollständiger Name: CD93 molecule
• Berechnetes Molekulargewicht: 69 kDa
• Beobachtetes Molekulargewicht: 120 kDa
• GenBank-Zugangsnummer: NM_012072.3
• Gene symbol: CD93
• Gene ID (NCBI): 22918
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein A purfication
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CD93, also known as C1qR or C1qR(p), is a single-pass type I transmembrane glycoprotein and a member of the group 14 of the C-type lectin-like domain (CTLD) superfamily, which also includes endosialin/CD248, thrombomodulin, and CLEC14A (PMID: 31287944). CD93 consists of a C-type lectin-like domain, five EGF-like repeats, a mucin-like domain, a transmembrane domain and a cytoplasmic domain (PMID: 28912033). CD93 is mainly expressed on endothelial cells and has been reported to be expressed by neurons and various cells of the hematopoietic system, including monocytes, neutrophils, B cells, natural killer cells, platelets and hematopoietic stem cells (PMID: 37443812). CD93 plays a role in various physiological processes including angiogenesis, inflammation, and cell adhesion (PMID: 31287944).