CD93 Rekombinanter Antikörper

CD93 Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

242464E6

Kat-Nr. : 98337-1-PBS

Synonyme

C1QR1, 242464E6, C1qR, C1qR(p), C1qRp

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  FC experiment of human PBMCs using 98337-1-RR (same clone as 98337-1-PBS)

  1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human CD93 Rabbit RecAb (98337-1-RR, Clone: 242464E6) or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were then stained with CoraLite® Plus 647 Anti-Human CD14. Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98337-1-PBS in a different storage buffer formulation.

• 

  FC experiment of human PBMCs using 98337-1-RR (same clone as 98337-1-PBS)

  1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human CD93 Rabbit RecAb (98337-1-RR, Clone: 242464E6) (red) or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98337-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

98337-1-PBS bindet in FC CD93 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: CD93 fusion protein Eg2794
• Vollständiger Name: CD93 molecule
• Berechnetes Molekulargewicht: 69 kDa
• GenBank-Zugangsnummer: NM_012072.3
• Gene symbol: CD93
• Gene ID (NCBI): 22918
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C.

Hintergrundinformationen

CD93, also known as C1qR or C1qR(p), is a single-pass type I transmembrane glycoprotein and a member of the group 14 of the C-type lectin-like domain (CTLD) superfamily, which also includes endosialin/CD248, thrombomodulin, and CLEC14A (PMID: 31287944). CD93 consists of a C-type lectin-like domain, five EGF-like repeats, a mucin-like domain, a transmembrane domain and a cytoplasmic domain (PMID: 28912033). CD93 is mainly expressed on endothelial cells and has been reported to be expressed by neurons and various cells of the hematopoietic system, including monocytes, neutrophils, B cells, natural killer cells, platelets and hematopoietic stem cells (PMID: 37443812). CD93 plays a role in various physiological processes including angiogenesis, inflammation, and cell adhesion (PMID: 31287944).